Beta-Alanine: The Science-Backed Supplement for Performance and Recovery
As physical therapists, we often emphasize the importance of proper training, recovery, and nutrition to optimize performance and reduce injury risk. While strength and endurance training play a crucial role, supplementation can offer additional benefits. One supplement gaining attention in the rehab and performance world is Beta-Alanine—a naturally occurring amino acid that enhances muscular endurance and delays muscle fatigue.
You may not recognize the name but if you’ve ever used pre-workout it is likely you’ve consumed it. It’s that special little ingredient that gives you the tingling sensation, yeah we all know that feeling, but there is much more to Beta-Alanine than that.
What is Beta-Alanine?
Beta-Alanine is a naturally occurring amino acid that works with histidine in the body to form carnosine, a compound stored in muscles. Carnosine helps reduce acid buildup during high-intensity exercise, which delays muscle fatigue and improves performance. This is especially beneficial for activities lasting 1-4 minutes, such as sprinting, HIIT workouts, or high-rep weightlifting.

Proven Benefits of Beta-Alanine for Performance
Beta-Alanine has been extensively researched, with a meta-analysis published in the Journal of the International Society of Sports Nutrition showing that supplementation can:
✅ Improve Muscular Endurance – Beta-Alanine increases intramuscular carnosine levels, which reduces lactic acid buildup and delays muscle fatigue, allowing for longer, more effective training sessions.
✅ Enhance High-Intensity Performance – Studies suggest a median improvement of 2.85% in exercise performance, particularly for high-intensity efforts lasting 30 seconds to 10 minutes.
✅ Support Injury Prevention & Recovery – By allowing for longer training sessions with less fatigue, Beta-Alanine may reduce the risk of overuse injuries and help support recovery in individuals returning from injury.
✅ Benefit Aging Populations – Carnosine levels decline with age, and Beta-Alanine supplementation has been shown to help maintain muscle function and overall physical capacity in older adults—an important consideration in rehabilitation and injury prevention.

Beta-Alanine vs. Creatine: Do You Need Both?
While Creatine enhances short bursts of power and strength by replenishing ATP, Beta-Alanine works by buffering acid buildup, improving endurance-based performance. Many athletes and rehab professionals use both supplements together to optimize strength, endurance, and recovery.
How to Take Beta-Alanine
📌 Dosage: The recommended dose is 3-6 grams per day, it is best divided into smaller doses (typically 3 a day, so 1-2 grams) to minimize the tingling sensation (paresthesia) that some people experience.
📌 Timing: Beta-Alanine works by building up carnosine stores over time, so daily intake is key—timing around workouts is less important than consistency. If it is in your pre-workout but you don’t take that every day then you should supplement outside of that on off days.
📌 Dietary Sources: While carnosine is found in meat and fish, supplementation is a more practical option for increasing muscle levels.
Who Can Benefit from Beta-Alanine?
✔ Athletes & Active Individuals – For those engaged in high-intensity training, Beta-Alanine improves endurance and workout capacity.
✔ Physical Therapy Patients – Those recovering from injury may benefit from improved muscular endurance and reduced fatigue during rehab.
✔ Older Adults – Helps maintain muscle function and slow age-related declines in physical performance.
Final Thoughts:
From a physical therapy standpoint, Beta-Alanine is a promising supplement for both performance enhancement and recovery. Whether you’re an athlete looking to push past fatigue or a rehab patient aiming to restore strength and endurance, Beta-Alanine may be a valuable addition to your regimen.
Sources:
Effects of β-alanine supplementation on exercise performance: a meta-analysis.